Posted By garyh I would contact the manufacturer or supplier of your gases, there will surely be a more modern SDS. As for your COSHH file, I would list all hazardsous substances, then make sure you have full hazard data (like the SDS). You then decide (document this!) which substances require full assessments. Acetone is highly flammable (not really a COSHH aspect, I know) and is I believe harmful and irritant. I would produce an assessment if I were you. I recall an incident a few years back where workers were using small amounts of Acetone but dispensing it from a 40 gallon (200l) drum ......... they had a serious spillage, which fired with severe consequences. The workers didn't really understand the hazards. My point is, they only used small amounts but they stored a drum of it - you need to look at the whole picture.

Posted By Chris Packham Remember that the Safety Data Sheet may not provide sufficient information for a COSHH risk assessment. Just look at paragraph 13 of the ACoP on COSHH for confirmation of this. You may need to request additional information from the supplier in order to comply with section 6-1 of the Health and Safety at Work etc. Act 1974. As far as acetone in nail varnish remover is concerned, I think you will find that a simple risk assessment indicates that the level of exposure, both respiratory and skin, is minimal so no significant risk.