Rank: Forum user 
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Hi all. We use isoflurane as an anaesthetic. It comes in 250ml bottles (glass). I'm currently doing the risk assessment for isoflurane/ anaesthesia procedures. One of the risks identified is a large spillage (a full glass bottle of 250ml dropped). There are WELs assigned to iso. For normal use we're well under the WEL (monitoring undertaken once a year). But if a bottle is dropped and smashed I’m struggling to understand when you'd deem that area safe to enter - and this will obviously change depending on the size of the room, ventilation/ extraction. But how would those on site (we ahve multiple sites) know when it's safe to go back into that area. Struggling a bit with the emergency spill procedure. Any comments are welcome. Thanks
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Rank: Super forum user 
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The gold standard would be a device that measures the airborne concentration, even in a rough and ready way such as a Draeger tube.
However presumably someone will need to go in to clear it up. For them you would ideally provide a suitable respirator.
I don't know this substance but you say it is an anaesthetic, so presumably you would be concerned about someone who went in losing consciousness. That is more of an issue than exceeding the WEL. Is there both a short term and a long term exposure limit? In that case the short term limit would be relevant to the clean-up operation and the long term limit to reoccupation.
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 1 user thanked Kate for this useful post.
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Rank: Super forum user
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If isoflurane is anything like halothane, then it is extremely volatile. This means if there is enough air changes in the room it will clear itself. How quickly it disperses depends on air changes, size of the room it has spilt in and temperature. If you really think that there is a serious risk of dropping the bottles you could put some transparent film around them to hold them together if they are dropped.
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1 user thanked A Kurdziel for this useful post.
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REPORTED AmandaWard hyperlink
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2 users thanked Roundtuit for this useful post.
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Rank: Super forum user
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REPORTED AmandaWard hyperlink
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2 users thanked Roundtuit for this useful post.
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I'm not famaliar with this substance, at our plant we have several flammable gasses and substances , we have fixed gas detection systems indicating safe to enter or not, with an audible and visual alarm. First point activation is 10% of the lower explosion limit and second at 20% , this could also be used as ppm.
Have you got LEV to clear the room
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1 user thanked Jonathan Bright for this useful post.
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Rank: Forum user
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Originally Posted by: Roundtuit  REPORTED AmandaWard hyperlink
Originally Posted by: Roundtuit REPORTED AmandaWard hyperlink @roundtuit - I'm not sure why you've reported my post?
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Rank: Super forum user
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@abotto I did not report your thread I reported a poster who saw it as opportunity to provide hyperlinks to matters unrelated to the discussion or general health & safety. We let others know suspicious links have been reported to save the moderators getting an avalanche of reports. When the moderators remove offending posts from a thread unfortunately there is a tendency to leave the report post behind.
To counter this inclusion of the name of the offending poster in your case AmandaWard lets the forum know who was reported. So no I did not report abotto
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Rank: Super forum user
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@abotto I did not report your thread I reported a poster who saw it as opportunity to provide hyperlinks to matters unrelated to the discussion or general health & safety. We let others know suspicious links have been reported to save the moderators getting an avalanche of reports. When the moderators remove offending posts from a thread unfortunately there is a tendency to leave the report post behind.
To counter this inclusion of the name of the offending poster in your case AmandaWard lets the forum know who was reported. So no I did not report abotto
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