Posted By Paul Leadbetter Simon The first question has to be 'is there a safer alternative'? If not, you need to consider the routes of exposure to the substances concerned. Are they volatile (in which case, you need to think about inhalation exposure) or not (in which case, you need to think about skin contact and, possibly, ingestion from contaminated hands or gloves)? While the initial two parts of the resin may present some risks, it is likely that the cured resin will present a much lower risk as the starting materials will have reacted together to produce the hardened filler, adhesive, or whatever. However, if the cured resin is to be sanded or otherwise abraded, you may need to consider inhalation of the particles. Contact me off-list if you need any further help in confidence. Regards Paul