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I need to know the TLV of Iodine but don't have a current list. Can anyone help or say if there is a website ?
Merv
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Rank: New forum user
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Rank: Super forum user
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WoW - what's a TLV - I guess it's a totally low-risk volume :)
I Google'd it and got - (Iodine) ACGIH TLV 0.1 ppm, lots of MSDS I only picked one at random. This would match the UK WEL - EH40 says:
Iodine 7553-56-2 - - 0.1 1.1 R20/21, 5
I always use http://esis.jrc.ec.europa.eu/ but it doesn't appear to give info on TLVs or WELs for iodine and I can't link you to the iodine page.... happy days.
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he didn't say - but I think he's in France -so EH40 is only good for a few tasks such as......
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Some of us remember from early childhood that iodine or perhaps a yellow paste made from the stuff was routinely available and used as a disinfectant/antiseptic (apologies for any incorrect terminology) for skin grazes, cuts and for stitched skin after surgery. It had quite a sting and probably stained clothing as well, but was apparently very effective. Though this nugget of information doesn't specifically answer the query posed, it may still have some peripheral relevance. Furthermore, though my memory might be playing tricks, I recall seeing seeing an article recently which described how iodine is now making a comeback in medicine, perhaps including as protection against MRSA. As I've no time to do an internet search now (about to go out to do an investigation), please can better informed forum users confirm or deny this aspect?
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To get Friday underway...
If maggots and honey (seriously!!) are making a come back I am sure Iodine might be in the revived list too :)
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teh_boy wrote:To get Friday underway...
If maggots and honey (seriously!!) are making a come back I am sure Iodine might be in the revived list too :)
Bring back Isopropyl Alcohol 70%bv! That's what I say!
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Thanks everyone.
Now, is anyone up for the LD50 ?
Merv
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Rank: Super forum user
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Iodine: ORAL (LD50): Acute: 14000 mg/kg [Rat]. 22000 mg/kg [Mouse]. Source Sciencelab.com
The data provided is for the element, not a compound.
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Rank: Super forum user
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This seems a ridiculously lazy way to use Google - getting others to do it for you when there is no reason not to do it oneself. It seems to be so common here.
However, to answer Graham's question concerning iodine as an antiseptic, yes, it was a good old standby and one that had never gone away. Perhaps the belief that it had been lost into the history of medicine is on the basis that OTC topical applications such as iodine creams and as tincture of iodine have been superseded by products for which staining of skin and clothing is less problematic.
We still use iodine formulations as a topical antiseptic in cream and liquid forms, and for more heavy duty skin disinfection prior to surgery, even for irrigation of the abdominal or chest cavities in some circumstances. The potency is high and the spectrum of activity is wider that most alternatives. Modern formulations are non-irritant.
Formulations can be alcoholic or aqueous, and with a detergent base it makes a supremely effective antiseptic for hand and forearm scrub for use by the surgical team.
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Rank: Super forum user
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Ian.Blenkharn wrote:This seems a ridiculously lazy way to use Google - getting others to do it for you when there is no reason not to do it oneself. It seems to be so common here.
You're in a real grump tonight Ian. That's three grumpy posts one after another. Perhaps you should find another outlet for your frustations. Seriously.
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I had tried google and wicki before coming up here, and acgih. The HSE link did give me the answers to TLV but then I needed LD50 as well and couldn't find it so came back here. I wasn't being lazy, just going to a source that I knew would help.
Thanks Stuff and others.
14 gms per kilo seems rather a lot especially for something which is a very effective antiseptic ?
Merv
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Rank: Super forum user
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It's Friday so...I asked the waiter for iodine and I dined alone...anyone remember that line?
Your red scarf matches your eyes, please close the cover before striking...
From memory, I didn't even ask another forum member to Yahoo! it for me (blatant plug there for another search engine).
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Rank: Super forum user
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Ian.Blenkharn wrote:This seems a ridiculously lazy way to use Google - getting others to do it for you when there is no reason not to do it oneself. It seems to be so common here.
.
Sometimes you just need a push in the right direction - I have got stuck looking for stuff and some of us just might know the answer -nowt wrong with being lazy :)
When it's a regular forums contributor like Merv who posts positive and informative posts I am more than happy to help.
Note: Google is full of miss information and people may have links to technical web sites that are known to be accurate!!!
Chin up - we've made it to Friday!
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Rank: Super forum user
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TLV is an Americanism- it is not a legal requirement even over their so why are you worrying about it?
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Ian B - Thanks for your information about iodine and correcting my misperception about its use as a disinfectant. Presumably OTC means 'over the counter'.
Also though all the chemical elements classed as halogens (4 from my recollection of 'O' level chemistry many years ago) apparently have antiseptic properties, is it the case that iodine is the least vicious to users and/or most effective as an antiseptic in contact with people or is it the case that its concentrations for such use are carefully controlled?
In addition, irrespective of whether or not I'm among those accused of laziness regarding internet searching, my response is that the internet contains some useful information - and also a lot of nonsense and misinformation. Therefore, sometimes such searches can be quite time-consuming because they involve looking at a number of websites in order to sensibly compare and evaluate their information. The same surely applies to information and opinions posted on this discussion forum! This is why I've suggested from time to time that IOSH should reinstate from the forum's former format the standard warning to users about not relying on its contents when making decisions, etc.
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Rank: Super forum user
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Rank: Forum user
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I finally thought to ask Jeeves (ask.com) and they/he gave a list of about 10 sources and values for LD50, all different, ranging from 500 to that 14000 mg/kg on a Merck website. Most seem to be in the 5-7000 range.
Still haven't found an authoritative source.
Could be a purple or burnt sienna Xmas for someone.
Thanks again everyone
Merv
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Rank: Super forum user
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This is not what you need on a Friday.
Get the cas number
Go to EU website I linked to
Search by cas number
Click on Iuclid tab - far right
Find iodine
Download insane datasheet and hope it contains ld info........
Have fun ;-)
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Rank: Super forum user
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quote=Graham Bullough]Presumably OTC means 'over the counter'.
Yes, over the counter
Iodine is the most appropriate halogen for use as an antiseptic. As always, there must be a balance between toxicity and other [generally adverse] properties and the antimicrobial action of a halogen or other chemical species. Parenthetically, the same is true of all drugs whether they be antimicrobials or otherwise.
Iodine is the only halogen suitable for use on the body. Chlorine is more aggressive, yet more powerful - school chemistry lessons will have taught of its greater reactivity - and is great for sanitising toilet bowls but not as an antiseptic for skin application. Take care not to splash bleach on the toilet seat, you will find out why this is so!
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Rank: Super forum user
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Yay, we did it!
That was hardcore.... My link contains more info than you can shake a stick at
Now where's the wine?
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Ian B - thanks for your useful information at #21.
As for chlorine, though most swimming pools are treated with chlorine, usually in the form of sodium hypochlorite, I guess that swimmers tend not to affected by swimming in what is presumably a bleach solution because it is greatly and sufficiently diluted. The same goes for bromine which tends to be the disinfecting agent used in small therapeutic pools. As I've forgotten the pool dilution levels involved for chlorine and bromine, please could more knowledgeable forum users advise what they are?
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Rank: Super forum user
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For tanked recirculating recreational waters the chlorine concentration is in the range 1-4 mg/l depending on pH, the use of stabilisers and predicted loading.
A dab of iodine ointment on a superficial wound or iodine skin scrub is formulated to deliver 1% and 10% iodine respectively.
Greater reactivity, lesser concentration, with some allowance for volatility and patterns of exposure (eyes) etc
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