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Fit testing for respirators - a cautionary tale
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Re fit testing The following is taken from a document produced by the British Association of Dermatologists on occupational skin disease during the coronavirus pandemic. <quote> Contact urticaria was seen in a nurse in Wales being “fit tested” for a face mask. The chemical used for the testing is denatonium benzoate, which has been previously reported to cause urticaria and asthma. <unquote> Worth checking your safety data sheet?
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Rank: Super forum user
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Denatonium Benzoate better known as Bitrex, which is the agent I use when face fit testing as it is easier for the user to detect that the sweet solution(saccharine?). Urticaria is also known as hives. Edited by user 29 April 2020 10:27:10(UTC)
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Rank: Super forum user
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I've always used saccharine in the first instance as Bitrex is so unpopular, with Bitrex as the second resort for those that don't detect the saccharine.
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1 user thanked Kate for this useful post.
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Rank: Super forum user
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Having just looked at the safety data sheet on one product recommended for fit testing I found it contained benzemethanamine (aka benzylamine. Whilst this is not officially classified at H317 it does appear in Anton de Groot's work on patch testing as recognised by dermatologists as a skin sensitiser capable of causing a type IV immune response (allergic contact dermatitis) and for which a patch testing recommendation exists.
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Rank: Super forum user
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Rank: Super forum user
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Rank: Super forum user
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Yes, but contains more than one constituent recognised by dermatologists as a skin sensitiser but which, for some reason, do not appear to fit the requirement for them to be classified as H317. Perhaps another reason why relying on safety data sheets for the information for a COSHH risk assessment might not be the way to go.
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Rank: Super forum user
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Originally Posted by: chris.packham Having just looked at the safety data sheet on one product recommended for fit testing I found it contained benzemethanamine (aka benzylamine. Whilst this is not officially classified at H317 it does appear in Anton de Groot's work on patch testing as recognised by dermatologists as a skin sensitiser capable of causing a type IV immune response (allergic contact dermatitis) and for which a patch testing recommendation exists. So on a legal point of view, do you take Anton de Groot or EH40 as guidance?
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Rank: Super forum user
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As always you do the risk assessment using whatever information is to hand. If EH40 says it’s a skin sensitisers that means it might cause problems if the person is a) susceptible and b) has repeated exposure. You can’t tell if a person is susceptible but you can always ask. You could arrange allergy testing but that might not be classed as reasonably practicable of you have loads of people and you only expose them to the Bitrex once a year or how often you do the face fit testing. If you decide that you don’t want to risk people developing urticaria, which is a kind of skin rash your options are: - Don’t do face fit testing- of course you should be doing face fit testing but decide how often you need to do it or look at alternative RPE that does not require face fit testing or good back to that original COSHH risk assessment and see if you can use other, better controls such as LEV.
- If you do a lot of face fit testing it might make sense to invest in a quantitative testing kit rather than the qualitative kit
- Or do what Kate says- reserve the Bitter solutions for those people who can’t taste the sweet solutions. The SDS for saccharin seems to indicate that it poses a minimal risk but there has been evidence that it might cause allergic reactions, which of course might be an issue with repeated exposure.
So you takes your money and makes your choice.
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Rank: Super forum user
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As far as my work is concerned EH40 is largely irrelevant. It is concerned with exposure limits for airborne exposure for the prevention of respiratory effects. The sk notation only applies to those substances that have a workplace exposure limit and that can penetrate the skin. There are no exposure limits for skin nor is there any validated method of measuring skin exposure. “However, there is no scientific method of measuring the results of the body’s exposure to risk through dermal contact. Consequently no dermal exposure standards have been set.” - from “Occupational skin diseases and dermal exposure in the European Union (EU-25):policy and practice overview - European Agency for Safety and Health at Work Furthermore, airborne skin exposure can cause damage to health in certain circumstances even though it is below the WEL. “Air threshold limits are insufficient to prevent adverse health effects in the case of contact with substances with a high dermal absorption potential.” - Drexler H, Skin protection and percutaneous absorption of chemical hazards, Int. Arch Occup. Environ. Health (2003) 76:359-361 Also, the fact that a substance has not been assigned a Hazard Statement does not mean that it cannot be a hazard to health under certain conditions – see COSHH regulation 2(1). Water (wet work) is the most common cause of occupational contact dermatitis. In my work I have to be guided by the scientific evidence relevant to the interaction between the skin and the (working) environment.
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Rank: Super forum user
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Allergy testing for skin reactions is not something that should be done as a precautionary measure. With both types of common allergy test (patch test for allergic contact dermatitis, prick test for allergic contact urticaria) there is always a risk of the person becoming sensitised. As the process of sensitisation takes days, your test would not reveal this but would return a negative result in someone not already sensitised. Sensitisation is asymptomatic so you would not be aware that this has happened. However, when next exposing that person to the sensitiser they might then respond with an allergic reaction. There are tests for type I immune response (allergic contact urticaria) which involve taking a blood sample and analysing this (ELISA, RAST) but these are expensive and not all that reliable.
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Fit testing for respirators - a cautionary tale
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